Twelve large pandemic events with at least 100,000 deaths Event Start End Deaths

https://en.wikipedia.org/wiki/List_of_epidemics and references therein.

Table 1: 

Twelve large pandemic events with at least 100,000 deaths Event Start End Deaths

Black Death 1331 1353 75,000,000

 Great Plague of London 1665 1666 100,000

First Asia Europe Cholera Pandemic 1816 1826 100,000

 Second Asia Europe Cholera Pandemic 1829 1851 100,000

Russia Cholera Pandemic 1852 1860 1,000,000 Global Flu Pandemic 1889 1890 1,000,000

Sixth Cholera Pandemic 1899 1923 800,000

 Encephalitis Lethargica Pandemic 1915 1926 1,500,000

 Spanish Flu 1918 1920 100,000,000

 Asian Flu 1957 1958 2,000,000 Hong Kong Flu 1968 1969 1,000,000

 H1N1 Pandemic 2009 2009 203,000 Source: